Charles W. Moore

Occasional thoughts and deeds
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  • Liking You Better

    Posted on October 17th, 2016 cwmoore No comments

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  • EAA Chapter 2

    Posted on October 2nd, 2016 cwmoore No comments

    We went to the 60th anniversary of EAA Chapter 2 and Met up with Les Zehr my original aviation mentor. He was well honored tonight for his long time contributions to grassroots aviation. An added item, that was asurprise to me, was that all past officers were invited to stand for pictures with Les and present officers. So I stood with them as an officer from 1969 – 1974. We enjoyed ourselves immensely, so much so that I re-upped with both EAA National & Chapter 2.  My EAA number is rather low by today’s numbers in the millions: Mine is in the 58K range as I snobbishly tell interested pilots.


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  • Indiana in perspective

    Posted on August 18th, 2016 cwmoore No comments

    It would take a lifetime to describe Indiana and even just NE Indiana where I live.  However, I came across this little article that shows some of it and I am ashamed to say I have been to less than half of the places.  So on the road with CWM: A Quick Tour Of Indiana.  Yes, the link is legitimate and takes you to a tour of Indiana’s natural resources and it opens in a new tab so so this blog stays open.  Try it but before your do here is a preview. My favorite lake in the summer – Lake Michigan.  This was our sailing grounds for many years and had many a fine cruises of a month duration.IndianaDunes


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  • Maybe I am not so brilliant

    Posted on August 17th, 2016 cwmoore No comments

    Ok, just when I think i am pretty smart or was really smart in my 30’s, along comes some really amazing things that make you re-think your own brilliance.  For example, neural dust device or how about Synthetic Biology.  All this technology is so amazing and  mind boggling that at times I wish I was thirty again.

    Synthetic biology is a highly interdisciplinary field, which combines biology, chemistry and physics with engineering. Its goal is to design molecular factories and synthetic cells with novel properties or functions for applications in healthcare, industry, or biological and medical research. Such artificial systems are in the nanometer scale and are built by combining and assembling existing, synthetic or engineered building blocks (e.g., proteins). Molecular systems have wide application ranges, e.g., for chemical compound synthesis, waste disposal, energy supply and medical diagnosis or treatment.

    Berkeley engineers have built the first dust-sized, wireless sensors that can be implanted in the body, bringing closer the day when a Fitbit-like device could monitor internal nerves, muscles or organs in real time. Wireless, batteryless implantable sensors could improve brain control of prosthetics, avoiding wires that go through the skull. (UC Berkeley video by Roxanne Makasdjian and Stephen McNally) Because these batteryless sensors could also be used to stimulate nerves and muscles, the technology also opens the door to “electroceuticals” to treat disorders such as epilepsy or to stimulate the immune system or tamp down inflammation.

    All this makes me wish I was working again – almost.

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  • My Brilliant Ideas

    Posted on August 11th, 2016 cwmoore No comments

    I have been studying DNA lately and am now reading the book “The Seven Daughter of Eve” by Bryan Sykes.The way he presents things is so clear and easy to read. The complexity of the process but the simplicity of the concept have made clear to me how to reconcile my strong belief in Science and an even stronger belief in the religious aspects. But why does this clarity always happen at 0430?

    I think there is a reason – your mind distills the days perplexing tasks and gives you the answer.  Many times in my life I have had a complex task to perform left over from the day before.  In a stroke of genius, the next morning I have an answer that seems so obvious I wonder why I did not think of it before.  One of those Test Answers:  If you know most of the answers the test was easy but if you did not then the test was hard.

    Ok, Moore later I think.

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  • Allstar Node 43584

    Posted on August 3rd, 2016 cwmoore No comments

    My second Allstar node is on the air and sounds good – incoming and outgoing – so all that remains now is for me to add the wireless interface software for connecting to my hotspot.  When finished I can talk anywhere in the world on my ham radio walkie talkie.  It does not seem too difficult but it really is a challenge to accomplish.  Even now I am tweeking the node.

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  • My Morning: Deer Population in Indiana & Human DNA

    Posted on July 18th, 2016 cwmoore No comments

    This area of short study was started when I read of 110,000 Moose in Newfoundland or was it Labrador?  Anyway, I was going to make a comment so I started looking up the number of deer in indiana.  They too have a Moose problem like we have a deer problem.  It is worth the read if you do not believe in hunting or even if you do.  Hopefully the pdf stays at this url for a long time  deerpopulationissues or .

    After that I came across the references to “The Lost Tomb of Jesus” docu-drama.  This lead to a long read by some scholarly people at  Apologetics Press and is quite good.  I almost bought the book but now I am glad that I read this article first.  I saved some money and reading time.  During this time, Steve, my PhD friend from St. Petersburg and amateur radio talk mate discussed  Mitochondrion DNA, which he finds fascinating.  It is a complicated subject and filled with hundreds of new mnemonics and terminology so only the upper 0.1% would like to try this one; however, I would like to know more.  Maybe there is a “Dummies Guide to Mitochondrion DNA”? Ah well. I guess I make fun of myself.

    Steve lead me to a new potential to start this area of layman’s study (Mitochondrion DNA):  Seven Daughters of Eve .  I put the book on my Amazon Used Book list and will buy on my next purchase.  I think people with an interest and aptitude have an obligation to human society to pursue quests of this sort that expands our general knowledge and promotes civilization. I cannot wait to order it and am excited about reading it.



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  • My Love/Hate: Relationship with Facebook

    Posted on July 5th, 2016 cwmoore No comments

    Sometimes I get so angry with the ill though out comments on Facebook.  Today, it was an old friend stating that Mr. Trump was good because ________ (fill in the blank).  This particular guy is the law and order type and a longtime friend.  This drove me over the edge and I made a comment saying both candidates are about the same as far as stretching the truth and just plain lying.  However, I will temper that by stating Mr. Trump may not even know he is lying and is so pathological about it that he will say anything to achieve his end game.  I think everyone knows that Clinton’s are lairs to a degree.  This friend’s statement came about because of the Clinton email issue and use of her personal server – which was an ill advised but clever circumvention of the rules – and the FBI investigation results.  He and many other of my friends do not like the results of the investigation so are pouting so to speak.  Who cares anyway?  Use of the “Classified” stamp is way to discretionary and cavalier anyway.  In the old days, I could put a Confidential or Secret or Top Secret or Need To Know stamp on any document I generated at a whim – there was no penalty for doing it as long as you were using your best judgement in doing it.  So someone over in the land of secrecy could label a document or email with anything the order of the day said to label it with or even label it as they thought was best or take the easy route and label everything with a classified label.  In this day and age almost everything becomes public knowledge sooner or later and the bad guys know details way before the public anyway.  So I say why make a big deal of this but they want political tools so they will grasp at straws.

    I listened to a podcast this morning using OSMC Raspberry Pi Server I have hooked up to the TV.  The gist of the discussion was that the working class Americans are so fed up with the “devils they know” in public office that they are supporting “the devil they do not know”.  The podcast made no apologies for this behavior nor did they support it and said that is the way it is.period. I have to agree!  Why? Because I feel that way myself.  A few long months ago, when asked who I would vote for, I answered with either Bernie or Trump as more or less a joke.  The joke became real and now it is not so funny and, in fact, is down right dangerous to our national and world identity.  However, I do not think there is any question as to who would be able to get things done in government effectively. This election will be the watershed election of my lifetime and, in the end, probably will not make a whit of difference in long term betterment of the American people no matter which is elected.  Personally, I think a moderately social and fiscally Conservative Libertarian would be the best course of action but that is not going to happen any time soon.  In the mean time, I think I will order the years supply of Food 4 Patriots 25 year shelf life dried MRE’s.

    I think I am becoming a cynic. Good bye for now but do try and make the OSMC Server as it is cheap and easy too and worth the effort.  I guess I got off track of my FB rant but at least I tried to explain myself and that is more than most will do.

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  • Colchicine for Gout Treatment

    Posted on May 11th, 2016 cwmoore No comments

    I found this very interesting article and the surprise in the concluding paragraph.  The URL to the subject is  The article, in part, concluded, from editorial comment,  that lowering serum levels may be a more effective treatment than anything but low doses of Colchicine (two 0.6 Mg then one 0.6 mg later).  Please read the article copied from the above link to form your on opinion. A big thanks to the researchers for this study.


    Optimal Colchicine Dosage for Acute Gout Explored



    Despite being used for decades as a primary treatment for acute gout, optimal colchicine dosing has not been systematically evaluated.  This is potentially important, as higher doses of colchicine can frequently be associated with the undesired consequence of severe diarrhea and gastrointestinal distress.  Here, Terkeltaub et al (Arthritis Rheum 2010; 62(4): 1060) explore different dosing strategies for colchicine in the first randomized, blinded, placebo controlled trial, named AGREE (Acute Gout Flare Receiving Colchicine Evaluation)


    Adult men and postmenopausal women with confirmed gout and a history of frequent flares were randomized to one of three treatment groups:

    1. low dose colchicine- 1.2 mg followed by 0.6 mg in one hour (followed by placebo doses on subsequent hours): total dose=1.8 mg
    2. high dose colchicine – 1.2 mg followed by 0.6 mg per hour for 5 hours: total dose 4.8 mg
    3. all placebo

    Participants were enrolled at 54 centers in the U.S. in 2007-2008.  Patients used supplied study medications within 12 hours of the onset of flare symptoms, with symptoms monitored in a diary.  Post-flare study visits were planned for within 48 hours of flare onset.  The primary endpoint was the proportion of patients with a 50% or greater reduction in pain within 24 hours of study drug.


    Among the 575 randomized patients, 185 had a gout flare and used the study medication.  There were 52 (28%) in the high dose group, 74 (40%) in the low dose group, and 59 (32%) in the placebo group.  Mean age was 52 years, with the majority of participants being male (95%), Caucasian (83%), with longstanding gout.  Tophi were uncommon (9%).  Despite a mean serum urate concentration of 8.8 mg/dl, less than a third were receiving urate lowering therapy.

    Table. Efficacy Outcomes According to Treatment Allocation

    High Dose

    Low Dose


    p-value high dose vs. placebo

    low dose vs. placebo

     50% reduction in pain at 24 hours






    ≥ 50% reduction in pain at 32 hours






    ≥ 2 unit reduction in pain at 24 hours






    ≥ 2 unit reduction in pain at 32 hours






    Rescue medications were used significantly less frequently in the colchicine groups, and did not differ by low-dose vs. high-dose allocation.

    For safety, there were no serious adverse events.  Diarrhea was observed in 77% of high dose colchicine treated patients compared to 23% of low-dose and 14% of placebo treated patients.  Severe diarrhea was observed in 19% of high dose patients, compared to none in the other groups.  Vomiting was only observed in the high dose colchicine group.  These differences were all statistically significant.


    Low dose colchicine was as efficacious as high dose in relieving the pain of recurrent gout flares with a more favorable side effect profile.

    Editorial Comment

    Colchicine has been widely used to treat acute gout for decades, yet its usage has been based primarily on style than hard data.  This study definitively supports the use of this low dose regimen over higher doses.  Even with higher doses, more than 60% of patients did not have at least a 50% reduction in the their symptoms in the first 24-32 hours.  This suggests that chronic urate lowering, rather than flare management, should be the focus of care in patients with frequent attacks, a modality that was absent in many of these patients.  Whether other treatments for acute gout (i.e. NSAIDs or glucocorticoids) are superior to this regimen has not been studied.

    End Quote

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  • Posted on April 28th, 2016 cwmoore No comments looks like a good trip to take for a retired family.  I am putting it on my to-do list.  If we get our RV then this is a definite for the late August or pre-colors season.  We get an all day train ride and a casino stay for a pretty cheap price.  I am no much of a gambler so they won’t make too much from me 🙂



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